SOX2 blocking peptide product blogThe SOX2 sox2 (Catalog #MBS9224512) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The SOX2 sox2 product has the following accession number(s) (GI #1351091) (NCBI Accession #P48431.1) (Uniprot Accession #P48431). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Cellular Location: Nucleus. Brain, Ear, Embryonic Tissue, Eye, Lung, Mouth, Muscle, Pituitary Gland, Placenta, Testis tissues are correlated with this protein. Breast Neoplasms, Carcinoma, Squamous Cell, Cell Transformation, Neoplastic, Lung Diseases, Lung Neoplasms, Neoplasm Invasiveness, Neoplasm Metastasis, Neoplasms, Experimental, Small Cell Lung Carcinoma, Thoracic Neoplasms are some of the diseases may be linked to SOX2 Antibody (Center) Blocking Peptide. The following patways have been known to be associated with this gene. SOX2 also interacts with the following gene(s): CDX2, FOXD3, KLF4, LIN28A, NANOG, PAX6, POU5F1, SALL4, ZIC3, ZSCAN10.