PTP1B recombinant protein product blogThe PTP1B ptpn1 (Catalog #MBS835967) is a Recombinant Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s PTP1B can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE.
One unit will hydrolyze 1nanomole of p-nitrophenyl-phosphatate per minute at pH 7.4 at 37 DEG C using 10mM of substrate. Researchers should empirically determine the suitability of the PTP1B ptpn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PTP1B ptpn1 product has the following accession number(s) (GI #169154359) (NCBI Accession #CAQ14262.1) (Uniprot Accession #B0S5X5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MEMEKEFEQI DKSGSWAAIY QDIRHEASDF PCRVAKLPKN KNRNRYRDVS PFDHSRIKLH QEDNDYINAS LIKMEEAQRS YILTQGPLPN TCGHFWEMVW EQKSRGVVML NRVMEKGSLK CAQYWPQKEE KEMIFEDTNL KLTLISEDIK SYYTVRQLEL ENLTTQETRE ILHFHYTTWP DFGVPESPAS FLNFLFKVRE SGSLSPEHGP VVVHCSAGIG RSGTFCLADT CLLLMDKRKD PSSVDIKKVL LEMRKFRMGL IQTADQLRFS YLAVIEGAKF IMGDSSVQDQ WKELSHEDLE PPPEHIPPPP RPPKRILEPH N.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given recombinant protein. We\'ve tested the PTP1B protein with the following immunoassay(s):
SDS-PAGE (Figure annotation denotes ug of protein loaded and % gel used.)
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including PTP1B are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Protein Type: Recombinant
Biological Significance: The protein coding region of the catalytic domain of PTP-1B (amino acids 1-321) was cloned into an E Coli expression vector. The catalytic domain of PTP-1B was overexpressed in E Coli as a soluble protein, and it was purified by conventional column chromatographic techniques.
Bioactivity: 10,000units/mg of PTP1B. Expression System: E Coli. PTP1B also interacts with the following gene(s): IRS1, IRS2, jak1, src, tyk2. Eye, Heart, Kidney, Muscle, Reproductive System, Whole Body tissues are correlated with this protein. The following patways have been known to be associated with this gene.