anti-FSCN1 antibody product blogThe FSCN1 fscn1 (Catalog #MBS530036) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Fascin antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Fascin can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB).
WB: 1:100-1:200. Researchers should empirically determine the suitability of the FSCN1 fscn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FSCN1 fscn1 product has the following accession number(s) (GI #4507115) (NCBI Accession #NP_003079.1) (Uniprot Accession #Q16658). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Mouse monoclonal Fascin antibody.
Biological Significance: Human fascin is an actin-bundling protein, whose actin binding ability is regulated by phosphorylation. In normal tissues the detection of fascin is reported to be predominantly restricted to dendritic cells and in the thymus has been observed only in medullary dendritic cells. However, in cases of Hodgkin\'s disease, including nodular sclerosis, mixed cellularity lymphocyte depletion and unclassified cases, most or all Reed Sternberg cells are reported to be positive for fascin. Fascin expression may be induced by Epstein-Barr virus (EBV) infection of B cells with the possibility that viral induction of fascin in lymphoid or other cell types must also be considered in EBV-positive cases. Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
Immunogen: Fascin antibody was raised in mouse using prokaryotic recombinant protein corresponding to the C-terminal region of the fascin molecule as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FSCN1 are readily searchable from our website. Different antibodies against the same target such as FSCN1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Breast Neoplasms, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms are some of the diseases may be linked to Fascin antibody. Bladder, Blood, Bone, Brain, Liver, Lung, Lymph Node, Muscle, Stomach, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene.