anti-CXCR4 antibody product blogThe CXCR4 cxcr4 (Catalog #MBS618545) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD184, NT (Fusin, LESTR, HUMSTR, C-X-C Chemokine Receptor 4) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CD184 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC).
Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry.
Dilution: Western Blot: 1:1000-1:2000
Immunohistochemistry: Frozen sections. Researchers should empirically determine the suitability of the CXCR4 cxcr4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CXCR4 cxcr4 product has the following accession number(s) (GI #56790927) (NCBI Accession #NP_001008540.1) (Uniprot Accession #P61073). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
CD184 (CXCR4) is a 40kD cell surface protein known to act as a co-factor in HIV infection of CD4+ T cells. Mutations in the CD184 gene are associated with WHIM syndrome, an inherited combined immunodeficiency disease.
Immunogen: Synthetic peptide corresponding to aa1-14 of human CD184. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CXCR4 are readily searchable from our website. Different antibodies against the same target such as CXCR4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Bone Marrow, Brain, Liver, Lung, Lymph, Lymph Node, Muscle, Vascular tissues are correlated with this protein. Breast Neoplasms, Cardiovascular Diseases, Inflammation, Ischemia, Lung Neoplasms, Necrosis, Neoplasm Metastasis, Neoplasms, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to CD184, NT (Fusin, LESTR, HUMSTR, C-X-C Chemokine Receptor 4). CXCR4 also interacts with the following gene(s): ADRBK1, CCL2, CD4, CXCL12, HIF1A, ITCH, PTPRC, RAC1, SDC4, UBC.