ZSTK474 kinase inhibitor product blog
Tags: Kinase Inhibitor; ZSTK474; ZSTK474 kinase inhibitor;
The ZSTK474 n/a (Catalog #MBS8506520) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given inhibitor. We\'ve tested the ZSTK474 with the following immunoassay(s):
Testing Data
ZSTK474 is an inhibitor of PI3K gamma (IC50 at 6 nM). This agent inhibits PI3K alpha and PI3K beta with IC50 of 17 and 53 nM, respectively. ZSTK474 was identified from a chemical library of about 1500 triazine derivatives, and selected for their ability to block tumor cell growth. In preclinical studies ZSTK474 was orally administered to mice and displayed a strong anti-tumoral activity in xenograft models. Toxicity was reported to be moderate. [1].
Solubility: DMSO >=21mg/mL - Water <1mg/mL - Ethanol <1mg/mL. Formula: C19H21F2N7O2
CAS Number: 475110-96-4.