Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource  rightarrow Blog  rightarrow XPO5 blocking peptide  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
 • ADAM28 shrna blog
 • anti-SFN antibody blog
 • ATP5J2 blocking peptide blog
 • CXXC5 sirna blog
 • anti-SPHK1 antibody blog
 • mmu-miR-467h mirna blog
 • Bradykinin peptide blog
 • CSNK1E recombinant protein blog
 • TNS3 sirna blog
 • mmu-miR-8102 mirna blog
 • BTG3 blocking peptide blog
 • RPS16 sirna blog
 • Ochratoxin A antibiotic blog
 • ESCO1 blocking peptide blog
 • anti-anti-Rat IgE antibody blog
 • ABCC9 sirna blog
 • PNPLA6 sirna blog
 • JADE2 shrna blog
 • OR7D2 shrna blog
 • anti-BAFF antibody blog
Blog Categories separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
Our Best Sellers moreseparator
 • HUWE1 Antibody
 • TMC8 Antibody
 • FAM208A Antibody
 • ZNT1 (SLC30A1) Antibody
 • cytochrome P450, family 39, subfamily A, polypeptide 1 (CYP3... ELISA Kit
 • MIP-1alpha ELISA Kit
 • VGLL3 Antibody
 • Histone H3R17me2a (HIST1H3A) Antibody
 • RICTOR Antibody
 downarrow more ...

XPO5 blocking peptide product blog

Posted on 2018-12-06 07:04:12 by mybiosource_staff
Share it on ...     
Tags: Blocking Peptide; XPO5; XPO5 blocking peptide;
The XPO5 xpo5 (Catalog #MBS9221393) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.

The XPO5 xpo5 product has the following accession number(s) (GI #74734245) (NCBI Accession #Q9HAV4.1) (Uniprot Accession #Q9HAV4). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Mediates the nuclear export of proteins bearing a double-stranded RNA binding domain (dsRBD) and double-stranded RNAs (cargos). XPO5 in the nucleus binds cooperatively to the RNA and to the GTPase Ran in its active GTP-bound form. Proteins containing dsRBDs can associate with this trimeric complex through the RNA. Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause disassembly of the complex and release of the cargo from the export receptor. XPO5 then returns to the nuclear compartment by diffusion through the nuclear pore complex, to mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Overexpression may in some circumstances enhance RNA-mediated gene silencing (RNAi). Mediates nuclear export of isoform 5 of ADAR/ADAR1 in a RanGTP-dependent manner.

XPO5 xpo5

Cellular Location: Nucleus. Cytoplasm. Note: Shuttles between the nucleus and the cytoplasm. Tissue Location: Expressed in heart, brain, placenta, lung, skeletal muscle, kidney and pancreas. Abnormalities, Multiple, Carcinoma, Squamous Cell, Cell Transformation, Neoplastic, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Disease Models, Animal, Kidney Diseases, Microsatellite Instability, Neoplasms, Experimental, Ovarian Diseases, Ovarian Neoplasms are some of the diseases may be linked to XPO5 Antibody (C-term) Blocking Peptide. The following patways have been known to be associated with this gene. Blood, Brain, Embryonic Tissue, Kidney, Liver, Lung, Muscle, Placenta, Stomach, Thyroid tissues are correlated with this protein. XPO5 also interacts with the following gene(s): DGCR8, DICER1, DROSHA, ILF3, NUP153, RAN, TARBP2.
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions