WYE-354 kinase inhibitor product blog
Tags: Kinase Inhibitor; WYE-354; WYE-354 kinase inhibitor;
The WYE-354 n/a (Catalog #MBS8506151) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given inhibitor. We\'ve tested the WYE-354 with the following immunoassay(s):
Testing Data
WYE-354, a cell-permeable pyrazolopyrimidine compound, is a potent and ATP competitive inhibitor of mTOR (IC50 = 5 nM), with significant selectivity over PI3K isofoms (>100-fold). When injected into tumor-bearing nude mice, WYE-354 inhibited mTORC1 and mTORC2 and displayed robust antitumor activity in PTEN-null tumors. [1].
Solubility: DMSO >=99 mg/mL - Water <1 mg/mL - Ethanol <1 mg/mL. Formula: C24H29N7O5
CAS Number: 1062169-56-5.