WWOX blocking peptide product blog
Tags: WWOX; Blocking Peptide; WWOX blocking peptide;
The WWOX wwox (Catalog #MBS544661) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s WWOX can be used in a range of immunoassay formats including, but not limited to, Immunocompetition, Immunodepletion.Western Blot: 1:500. Researchers should empirically determine the suitability of the WWOX wwox for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The WWOX wwox product has the following accession number(s) (GI #7706523) (NCBI Accession #NP_057457.1) (Uniprot Accession #Q9NZC7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Antigenic Blocking Peptide WW domain-containing Oxidoreductase isoform 1 Antibody
Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.
Immunogen: Synthetic Peptide
Expression: Widely expressed. Strongly expressed in testis, prostate, and ovary. Overexpressed in cancer cell lines. Isoform 5 and isoform 6 may only be expressed in tumor cell lines. Molecular Function: Coenzyme binding; protein dimerization activity; cofactor binding;
Structure: Interacts with TP53, p73/TP73 and MAPK8. Interacts with MAPT/TAU, RUNX2 and HYAL2 (By similarity). Forms a ternary complex with TP53 and MDM2. Interacts with ERBB4, LITAF and WBP1. Interacts with DVL1, DVL2 and DVL3. May interact with FAM189B and SCOTIN.
Subcellular Location: Cytoplasm. Nucleus. Mitochondrion. Golgi apparatus. Blood, Bone, Brain, Kidney, Liver, Lung, Lymph, Nerve, Ovary, Prostate tissues are correlated with this protein. WWOX also interacts with the following gene(s): ERBB2, ERBB4, EZR, MAPK8, SRC, TNK2, TP53, YAP1. Breast Neoplasms, Carcinoma, Cell Transformation, Neoplastic, Chromosome Aberrations, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Experimental, Nervous System Diseases, Ovarian Neoplasms are some of the diseases may be linked to WWOX 1/4 Antibody Antigenic Blocking Peptide. The following patways have been known to be associated with this gene.