Please refer to the product datasheet for known applications of a given antibiotic. We\'ve tested the Wortmannin (KY 12420, BRN 0067676, NSC 627609, Antibiotic SL-2052) with the following immunoassay(s): Structure (Structure of 045393)
Antibiotic. Potent anti-neutrophil agent with cardioprotective effects. mTOR, DNA-PK, phosphatidylinositol 4-kinases, myosin light chain kinase (MLCK) and mitogen-activated protein kinase (MAPK) inhibitor at high concentrations. Potent cell permeable and selective inhibitor of phosphatidyl-inositol 3-kinase (PI3K). Antitumor compound. Radiosensitizing agent. Adipogenesis inhibitor. Angiogenesis inhibitor. Autophagy inhibitor. DNA repair, receptor-mediated endocytosis and cell proliferation inhibitor. Potentiates the LPS-induced nitric oxide (NO) production from macrophages. Induces in vivo Alzheimer-like hyperphosphorylation in tau. Polo-like kinase family inhibitor.
CAS Number: 19545-26-7 Molecular Formula: C23H24O8.