|The VTCN1 vtcn1 (Catalog #MBS659589) is a Peptide and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s B7H4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA).
Suitable for use in ELISA. Researchers should empirically determine the suitability of the VTCN1 vtcn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The VTCN1 vtcn1 product has the following accession number(s) (GI #42357719) (NCBI Accession #AAS13400.1) (Uniprot Accession #Q7Z7D3). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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As a member of B7 family, B7-H4 (VTCN1) plays a critical role in the regulation of antigen-specific immune responses. B7-H4 is a co-stimulatory protein expressed in activated T cells and is involved in the negative regulation of cell-mediated immunity in peripheral tissues. B7-H4 ligation to its receptor BTLA T-lymphocytes results in inhibition of T-cell activation, cytokine secretion, and the development of cytotoxicity. B7-H4 protein is typically expressed on the surface of activated T-cells, B-cells, monocytes, and dendritic cells, but not in most normal
C-SKGKGNANLEYK, from the internal region of human B7-H4. Control peptide corresponding to polyclonal antibody, Catalog#B0000-35A, goat x human.
Bone, Embryonic Tissue, Kidney, Liver, Lung, Ovary, Pancreas, Placenta, Prostate, Uterus tissues are correlated with this protein. The following patways have been known to be associated with this gene. Adenocarcinoma, Disease Models, Animal, Encephalomyelitis, Autoimmune, Experimental, Endometrial Neoplasms, Hyperplasia, Kidney Diseases, Necrosis, Ovarian Diseases, Ovarian Neoplasms, Prostatic Diseases are some of the diseases may be linked to B7H4 (B7-H4, B7S1, B7x, BC032925, Immune Costimulatory Protein B7H4, MGC41287, PRO1291, T Cell Costimulatory Molecule B7x, V Set Domain-containing T Cell Activation Inhibitor 1, VCTN1) (Control Peptide). VTCN1 also interacts with the following gene(s): BTLA, CTLA4, PDCD1.