VKORC1 positive control product blog
Tags: VKORC1; Positive Control; VKORC1 positive control;
The VKORC1 vkorc1 (Catalog #MBS543372) is a Positive Control and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s VKORC1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Western Blot: 1:500. Researchers should empirically determine the suitability of the VKORC1 vkorc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The VKORC1 vkorc1 product has the following accession number(s) (GI #748806600) (NCBI Accession #AJE63371.1) (Uniprot Accession #Q6TEK4). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given positive control. We\'ve tested the VKORC1 Positive Control with the following immunoassay(s):
Western Blot (WB)
Western Blot Positive Control Vitamin K epoxide reductase complex subunit 1
Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2, 3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development.
Immunogen: Purified Protein
Expression: Highly expressed in liver. Detected at lower levels in lung, kidney and testis. Molecular Function: Oxidoreductase, Quinone binding, vitamin-K-epoxide reductase
Subcellular Location: Endoplasmic Reticulum membrane; Multi-pass membrane protein. Blood Coagulation Disorders, Coronary Disease, Coumarin Resistance, Drug-Related Side Effects and Adverse Reactions, Heart Diseases, Hemorrhage, Kidney Diseases, Liver Diseases, Stroke, Vascular Diseases are some of the diseases may be linked to VKORC1 Positive Control. Artery, Connective Tissue, Embryonic Tissue, Eye, Heart, Kidney, Liver, Lung, Placenta, Prostate tissues are correlated with this protein. VKORC1 also interacts with the following gene(s): Calu, Ggcx, Nqo1.