VCL blocking peptide product blog
Tags: VCL; Blocking Peptide; VCL blocking peptide; VINC;
The VCL vcl (Catalog #MBS9226882) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The VCL vcl product has the following accession number(s) (GI #21903479) (NCBI Accession #P18206.4) (Uniprot Accession #P18206). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
Cellular Location: Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, focal adhesion. Note: Cytoplasmic face of adhesion plaques. Recruitment to cell-cell junctions occurs in a myosin II- dependent manner. Interaction with CTNNB1 is necessary for its localization to the cell-cell junctions (By similarity) Colocalizes with LIMD1 in the focal adhesions. Tissue Location: Metavinculin is muscle-specific. Brain Diseases, Cardiovascular Diseases, Heart Diseases, Hypertension, Inflammation, Kidney Diseases, Lung Diseases, Lung Neoplasms, Neoplasm Metastasis, Nervous System Diseases are some of the diseases may be linked to VINC Antibody (N-term) Blocking Peptide. Blood, Bone, Brain, Heart, Kidney, Liver, Lung, Muscle, Testis, Vascular tissues are correlated with this protein. VCL also interacts with the following gene(s): ACTN1, CDH1, CTNNA1, PTK2, PXN, SRC, TLN1. The following patways have been known to be associated with this gene.