|The VAPB vapb (Catalog #MBS9223848) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The VAPB vapb product has the following accession number(s) (GI #24638339) (NCBI Accession #O95292.3) (Uniprot Accession #O95292). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.
Cellular Location: Endoplasmic reticulum membrane; Single-pass type IV membrane protein Note: Present in mitochondria-associated membranes that are endoplasmic reticulum membrane regions closely apposed to the outer mitochondrial membrane. Tissue Location: Ubiquitous. Isoform 1 predominates. VAPB also interacts with the following gene(s): FAM82A2, OSBP, TARDBP, VAPA, YIF1A, ZFYVE27. The following patways have been known to be associated with this gene. Bone, Brain, Eye, Liver, Lung, Lymph, Lymph Node, Muscle, Nerve, Vascular tissues are correlated with this protein. Adenocarcinoma, Amyotrophic Lateral Sclerosis 8, Atrophy, Chromosome Aberrations, Disease Models, Animal, Liver Diseases, Lung Diseases, Necrosis, Nerve Degeneration, Nervous System Diseases are some of the diseases may be linked to VAPB Antibody (C-term) Blocking Peptide.