|The UBE2D2 ube2d2 (Catalog #MBS9221069) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The UBE2D2 ube2d2 product has the following accession number(s) (GI #51338685) (NCBI Accession #P62837.1) (Uniprot Accession #P62837). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes \'Lys- 48\'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP- induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.
Brain Diseases, Cardiovascular Diseases, Disease Models, Animal, Learning Disorders, Memory Disorders, Movement Disorders, Nervous System Diseases, Neurobehavioral Manifestations, Neurodegenerative Diseases, Prenatal Injuries are some of the diseases may be linked to UBE2D2 Antibody (C-term) Blocking Peptide. Blood, Brain, Intestine, Kidney, Liver, Lung, Muscle, Placenta, Testis, Thymus tissues are correlated with this protein. The following patways have been known to be associated with this gene.