UBA6 blocking peptide product blog
Tags: Blocking Peptide; UBA6; UBA6 blocking peptide;
The UBA6 uba6 (Catalog #MBS9222082) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The UBA6 uba6 product has the following accession number(s) (GI #121949450) (NCBI Accession #A0AVT1.1) (Uniprot Accession #A0AVT1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin- E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Essential for embryonic development. Required for UBD/FAT10 conjugation. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility.
Tissue Location: Widely expressed. Isoform 2 is predominantly expressed in testis with higher expression in adult testis than in fetal testis. The following patways have been known to be associated with this gene. Fatty Liver, Learning Disorders, Liver Diseases, Liver Neoplasms, Necrosis, Weight Loss are some of the diseases may be linked to UBA6 Antibody (C-term) Blocking Peptide. UBA6 also interacts with the following gene(s): AIPL1, UBE2A, UBE2D2, UBE2Z. Brain, Embryonic Tissue, Eye, Liver, Nerve, Ovary, Testis, Uncharacterized Tissue tissues are correlated with this protein.