Tsc1 blocking peptide product blog
Tags: Blocking Peptide; TSC1; TSC1 blocking peptide; TSC1 (S555);
The Tsc1 tsc1 (Catalog #MBS9225326) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The Tsc1 tsc1 product has the following accession number(s) (GI #81868102) (NCBI Accession #Q9EP53.1) (Uniprot Accession #Q9EP53). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Cellular Location: Cytoplasm. Membrane; Peripheral membrane protein. Note: At steady state found in association with membranes. Brain, Embryonic Tissue, Eye, Heart, Kidney, Liver, Lung, Muscle, Pancreas, Skin tissues are correlated with this protein. The following patways have been known to be associated with this gene. Brain Diseases, Carcinoma, Renal Cell, Cardiovascular Diseases, Epilepsy, Kidney Diseases, Liver Neoplasms, Lymphangioleiomyomatosis, Neoplasms, Experimental, Tuberous Sclerosis, Tuberous Sclerosis 1 are some of the diseases may be linked to Phospho-mouse TSC1(S555) Antibody Blocking peptide. Tsc1 also interacts with the following gene(s): Akt1, Akt2, Akt3, Ikbkb, Mtor, Prkaa1, Rheb, Rps6kb1, Tsc2.