TRIP4 blocking peptide product blog
Tags: Blocking Peptide; TRIP4; TRIP4 blocking peptide;
The TRIP4 trip4 (Catalog #MBS9221858) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The TRIP4 trip4 product has the following accession number(s) (GI #116242828) (NCBI Accession #Q15650.4) (Uniprot Accession #Q15650). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation (PubMed:10454579, PubMed:25219498). Also involved in androgen receptor transactivation (By similarity). Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF- kappa-B (PubMed:12077347).
Cellular Location: Nucleus. Cytoplasm, cytosol Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note: Cytoplasmic under conditions of serum deprivation (PubMed:10454579). Colocalizes with NEK6 in the centrosome (PubMed:20873783). Blood, Bone, Brain, Embryonic Tissue, Esophagus, Liver, Muscle, Stomach, Testis, Thyroid tissues are correlated with this protein. Brain Diseases, Weight Loss are some of the diseases may be linked to TRIP4 Antibody (Center) Blocking Peptide.