|The Trag-3 n/a (Catalog #MBS396455) is a Peptide and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Trag-3 can be used in a range of immunoassay formats including, but not limited to, Antibody Function Blocking. Researchers should empirically determine the suitability of the Trag-3 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
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The expression of the cancer-testis antigen Taxol resistance-associated gene-3 (TRAG-3) is associated with acquired paclitaxel (Taxol) resistance, and is expressed in a variety of cancers - e.g., breast cancer, leukemia, and melanoma. Overexpressed in taxol-resistant breast cancer line MDA 435(TR) and the doxorubicin-resistant multiple myelanoma lines 8226/Dox(40) and 8226/MDR(10)V. Weakly expressed in kidney. TRAG-3 is an attractive target for immunotherapy of cancer.