|The TPPP tppp (Catalog #MBS9222252) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The TPPP tppp product has the following accession number(s) (GI #28380097) (NCBI Accession #O94811.1) (Uniprot Accession #O94811). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.
Cellular Location: Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Note: Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies. Tissue Location: Widely expressed. Blood, Brain, Intestine, Kidney, Lung, Nerve, Ovary, Pancreas, Skin tissues are correlated with this protein. The following patways have been known to be associated with this gene. TPPP also interacts with the following gene(s): GAPDH, LIMK1, ROCK1, SNCA. Atrophy, Memory Disorders, Mental Disorders, Necrosis, Neoplasm Metastasis, Neoplasms, Experimental, Nerve Degeneration, Nervous System Malformations, Neurobehavioral Manifestations, Prenatal Exposure Delayed Effects are some of the diseases may be linked to TPPP Antibody (Center) Blocking Peptide.