|The TNFa tnf (Catalog #MBS343141) is a Western Blot Control and is intended for research purposes only. The product is available for immediate purchase.
The TNFa tnf product has the following accession number(s) (GI #37210) (NCBI Accession #CAA26669.1) (Uniprot Accession #P01375). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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TNF alpha is a potent pleiotrophic cytokine, produced by white blood cells, endothelium and several other normal and Tumor cells in response to a wide variety of stimuli. TNF alpha is involved in the pathophysiological processes of several chronic and acute diseases including the induction of apoptosis and up regulation of inflammation. Recombinant TNF alpha comprises a 157 amino acid fragment (77-233) corresponding to the mature soluble TNF alpha chain protein. TNF alpha is expressed in E Coli with an amino-terminal hexahistidine tag. This product is not intended for therapeutic use.
Buffer: Buffered 50% glycerol. Atherosclerosis, Colitis, Fibrosis, Inflammation, Insulin Resistance, Liver Diseases, Lung Diseases, Necrosis, Pain, Reperfusion Injury are some of the diseases may be linked to Tumor Necrosis Factor Alpha (TNFa) (Western Blot Control). Blood, Brain, Connective Tissue, Heart, Intestine, Lung, Lymph Node, Ovary, Placenta, Prostate tissues are correlated with this protein. The following patways have been known to be associated with this gene. TNFa also interacts with the following gene(s): CD83, FOXP3, ICAM1, IFNG, IKBKG, ITGAM, MMP9, MYC, RELB, TNFRSF1A.