TNF recombinant protein product blog
Tags: TNF; Recombinant Protein; Tumor Necrosis Factor-alpha; TNF recombinant protein;
The TNF tnf (Catalog #MBS553156) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase.The TNF tnf product has the following accession number(s) (GI #7305585) (NCBI Accession #NP_038721.1) (Uniprot Accession #P06804). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MSTESMIRDV ELAEEALPQK MGGFQNSRRC LCLSLFSFLL VAGATTLFCL LNFGVIGPQR DEKFPNGLPL ISSMAQTLTL RSSSQNSSDK PVAHVVANHQ VEEQLEWLSQ RANALLANGM DLKDNQLVVP ADGLYLVYSQ VLFKGQGCPD YVLLTHTVSR FAISYQEKVN LLSAVKSPCP KDTPEGAELK PWYEPIYLGG VFQLEKGDQL SAEVNLPKYL DFAESGQVYF GVIAL.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Tumor Necrosis Factor-alpha are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Domain: TNF
Host Note: Optimized DNA sequence encoding Mouse Tumor Necrosis Factor-alpha extracellular domain was expressed in Escherichia Coli. Endotoxin: Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
Reconstitution: A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Molecular Weight Note: Native Mouse Tumor Necrosis Factor-alpha is generated by the proteolytic removal of the signal peptide and propeptide, this molecule has a calculated mass of approximately 17kDa.
Recombinant Mouse TNF is a disulfide-linked monomer protein, consisting of 157 amino acids and migrates as an approximately 17 kDa protein under reducing conditions. The following patways have been known to be associated with this gene. Arthritis, Rheumatoid, Cardiovascular Diseases, Infection, Inflammation, Leukemia, Liver Diseases, Lung Diseases, Neoplasms, Sepsis, Skin Diseases are some of the diseases may be linked to Mouse Tumor Necrosis Factor-alpha Recombinant. TNF also interacts with the following gene(s): Ddx5, Hnrnpd, Nono, Tial1. Bone Marrow, Embryonic Tissue, Joint, Lymph Node, Mammary Gland, Prostate, Skin, Spleen, Thymus, Uncharacterized Tissue tissues are correlated with this protein.