TLR1 blocking peptide product blog
Tags: Blocking Peptide; TLR1; TLR1 blocking peptide;
The TLR1 tlr1 (Catalog #MBS544573) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s TLR1 can be used in a range of immunoassay formats including, but not limited to, Immunocompeition, Immunodepletion.Immunocytochemistry: 1:100
Immunofluorescence: 1:100
Immunohistochemistry: 1:100
Western Blot: 1:500. Researchers should empirically determine the suitability of the TLR1 tlr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TLR1 tlr1 product has the following accession number(s) (GI #80475016) (NCBI Accession #AAI09094.1) (Uniprot Accession #Q15399). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Antigenic Blocking Peptide Toll-like receptor 1
Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.
Immunogen: Synthetic peptide taken within amino acid region 370-420 on human Toll-like receptor 1. Molecular Function: Receptor, Transmembrane signaling receptor activity, triacyl lipopeptide binding
Structure: Binds MYD88 (via TIR domains) (By similarity). Interacts (via extracellular domain) with TLR2. Ligand binding induces the formation of a heterodimer with TLR2 (By similarity). Interacts with CNPY3.
Subcellular Location: Cell membrane; Single-pass type I membrane protein, Cytoplasmic vesicle ; phagosome membrane; Single-pass type I membrane protein. TLR1 also interacts with the following gene(s): CD14, HMGB1, HSPD1, IRAK2, IRAK4, LY96, MYD88, TIRAP, TLR2. Bone tissues are correlated with this protein. The following patways have been known to be associated with this gene. Colitis, Heart Diseases, Inflammation, Kidney Diseases, Leprosy, Liver Diseases, Lung Diseases, Necrosis, Neoplasms, Experimental, Pneumonia are some of the diseases may be linked to TLR1 Peptide.