TLK1 blocking peptide product blog
Tags: Blocking Peptide; TLK1; TLK1 blocking peptide;
The TLK1 tlk1 (Catalog #MBS9227539) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The TLK1 tlk1 product has the following accession number(s) (GI #34223086) (NCBI Accession #Q9UKI8.2) (Uniprot Accession #Q9UKI8). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S- phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at \'Ser-10\'.
Cellular Location: Nucleus. Tissue Location: Widely expressed. Present in fetal placenta, liver, kidney and pancreas but not heart or skeletal muscle. Also found in adult cell lines. Isoform 3 is ubiquitously expressed in all tissues examined. Adenocarcinoma, Atrophy, Breast Neoplasms, Carcinoma, Fibrosis, Neoplasm Metastasis, Neoplasm Recurrence, Local, Neoplasms, Experimental are some of the diseases may be linked to TLK1 Antibody (C-term) Blocking Peptide. Liver, Mouth, Prostate, Salivary Gland, Testis, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene.