TIMP1 blocking peptide product blog
Tags: TIMP1; Blocking Peptide; TIMP1 blocking peptide;
The TIMP1 timp1 (Catalog #MBS9218219) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The TIMP1 timp1 product has the following accession number(s) (GI #135850) (NCBI Accession #P01033.1) (Uniprot Accession #P01033). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.
Cellular Location: Secreted. Tissue Location: Detected in rheumatoid synovial fluid (at protein level). TIMP1 also interacts with the following gene(s): MMP1, MMP10, MMP14, MMP15, MMP2, MMP3, MMP9, SERPINE1, STAT3, TGFB1. Cardiovascular Diseases, Female Urogenital Diseases, Fibrosis, Heart Diseases, Inflammation, Liver Cirrhosis, Liver Diseases, Necrosis, Neoplasm Invasiveness, Vascular Diseases are some of the diseases may be linked to TIMP1 Antibody (C-term) Blocking peptide. Blood, Bone, Brain, Connective Tissue, Heart, Kidney, Liver, Lung, Muscle, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene.