|The TIA1 tia1 (Catalog #MBS544563) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s TIA1 can be used in a range of immunoassay formats including, but not limited to, Immunocompeition, Immunodepletion.
Confocal Microscopy: 1:50
Western Blot: 1:500. Researchers should empirically determine the suitability of the TIA1 tia1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TIA1 tia1 product has the following accession number(s) (GI #62088002) (NCBI Accession #BAD92448.1) (Uniprot Accession #P31483). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Antigenic Blocking Peptide Nucleolysin TIA-1 isoform p40 Antibody
Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3\' untranslated regions (3\' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
Immunogen: Synthetic Peptide. Molecular Function: AU-rich element binding, nucleotide binding, poly(A) binding, poly (A) RNA binding
Subcellular Location: Cytoplasmic granule, nucleus. (Note: accumulates in Cytoplasmic stress granules following cellular damage. Blood, Bone, Bone Marrow, Brain, Kidney, Liver, Lung, Lymph Node, Skin, Spleen tissues are correlated with this protein. TIA1 also interacts with the following gene(s): COL2A1, EIF4G1, FASTK, G3BP1, GZMB, IL10, PTGS2. The following patways have been known to be associated with this gene. Adenocarcinoma, Atrophy, Brain Diseases, Fibrosis, Hyperplasia, Inflammation, Liver Diseases, Liver Neoplasms, Necrosis, Nervous System Diseases are some of the diseases may be linked to TIA1 Antibody Antigenic Blocking Peptide.