THOC3 blocking peptide product blog
Tags: Blocking Peptide; THOC3; THOC3 blocking peptide;
The THOC3 thoc3 (Catalog #MBS9222909) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The THOC3 thoc3 product has the following accession number(s) (GI #48474597) (NCBI Accession #Q96J01.1) (Uniprot Accession #Q96J01). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5\' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi\'s sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.
Cellular Location: Nucleus. Nucleus speckle. The following patways have been known to be associated with this gene.