THBS4 blocking peptide product blog
Tags: THBS4; Blocking Peptide; THBS4 blocking peptide;
The THBS4 thbs4 (Catalog #MBS9228596) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The THBS4 thbs4 product has the following accession number(s) (GI #31543806) (NCBI Accession #NP_003239.2) (Uniprot Accession #P35443). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload. May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury. May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner (By similarity).
Cellular Location: Endoplasmic reticulum. Sarcoplasmic reticulum. Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Brain Diseases, Disease Models, Animal, Fibrosis, Heart Diseases, Hypertension, Hypertrophy, Inflammation, Lung Diseases, Nerve Degeneration, Vasculitis are some of the diseases may be linked to THBS4 Blocking Peptide(C-term). Blood, Bone, Brain, Connective Tissue, Heart, Kidney, Lung, Muscle, Prostate, Stomach tissues are correlated with this protein. The following patways have been known to be associated with this gene.