TGF b 1 native protein product blog
Tags: Native Protein; Transforming Growth Factor-Beta 1; TGF b 1 ; TGF b 1 native protein;
The TGF b 1 tgfb1 (Catalog #MBS143480) is an Active Protein produced from Human Platelets and is intended for research purposes only. The product is available for immediate purchase.The TGF b 1 tgfb1 product has the following accession number(s) (GI #63025222) (NCBI Accession #NP_000651.3) (Uniprot Accession #P01137). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Transforming Growth Factor-Beta 1 are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Physical Appearance: Sterile Filtered lyophilized powder.
Solubility: It is recommended to reconstitute lyophilized TGF-beta 1 in 0.5% BSA in 0.1N acetic acid, which can then be further diluted to the desired aliquot with 30% acetonitrile and 0.1% trifluoroacetic acid. Biological Activity: Stimulates the growth of NRK-1 cells in soft agar at concentrations ranging from 0.1 to 5ng/ml corresponding to a specific activity of 200,000-10,000,000IU/mg. Effective concentration ranges must be experimentally determined. Purified EGF and/or TGF-α must be present for observation of the biological activity. Blood, Bone, Bone Marrow, Connective Tissue, Heart, Kidney, Liver, Lung, Muscle, Skin tissues are correlated with this protein. The following patways have been known to be associated with this gene. TGF b 1 also interacts with the following gene(s): DCN, FN1, LTBP1, SMAD2, SMAD7, TGFBR1, TGFBR2, TGFBR3, TIMP1. Asthma, Diabetic Nephropathies, Fibrosis, Hypersensitivity, Hypertension, Liver Cirrhosis, Lung Diseases, Neoplasm Metastasis, Proteinuria, Pulmonary Fibrosis are some of the diseases may be linked to Human Transforming Growth Factor-Beta 1.