TF native protein product blog
Tags: Transferrin; Native Protein; TF native protein;
The TF tf (Catalog #MBS537635) is a Native Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Transferrin can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the TF tf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The TF tf product has the following accession number(s) (GI #248648) (NCBI Accession #AAB22049.1) (Uniprot Accession #P02787). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Transferrin are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Source Note: Human serum/plasma
Protein Type: Native
Biological Significance: Transferrins are iron-binding blood plasma glycoproteins that control the level of free iron in biological fluids. In humans, it is encoded by the TF gene. Transferrin is a glycoprotein that binds iron very tightly but reversibly. Although iron bound to transferrin is less than 0.1% (4 mg) of the total body iron, it is the most important iron pool, with the highest rate of turnover (25 mg/24 h). Biohazard Information: Donor samples were tested and found to be negative for HIV I/II, and HCV antibodies, and Hepatitis B surface antigen. Nonetheless caution should be used when handling this material as there is a margin of error in all tests. This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. TF also interacts with the following gene(s): ALB, APOA1, HEPH, HIF1A, IGFBP3, SLC40A1, TFR2, TFRC. The following patways have been known to be associated with this gene. Blood, Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Muscle, Nerve, Skin tissues are correlated with this protein. Atherosclerosis, Carcinoma, Cardiovascular Diseases, Immune System Diseases, Inflammation, Liver Diseases, Liver Neoplasms, Lung Neoplasms, Necrosis, Nervous System Diseases are some of the diseases may be linked to Transferrin protein.