|The TECK ccl25 (Catalog #MBS539500) is a Recombinant Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s TECK can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the TECK ccl25 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TECK ccl25 product has the following accession number(s) (GI #5881909) (NCBI Accession #CAB55762.1) (Uniprot Accession #Q9QYY6). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
Region of TECK protein correspond ing to amino acids QGVFEDCCLA YHYPIGWAVL RRAWTYRIQE VSGSCNLPAA IFYLPKRHRK VCGNPKSREV QRAMKLLDAR NKVFAKLHHN MQTFQAGPHA VKKLSSGNSK LSSSKFSNPI SSSRKNVSLL ISANSGL.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including TECK are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Protein Type: Recombinant
Biological Significance: TECK is a CC chemokine, specifically expressed by thymic stromal cells, and signals through the CCR9 receptor. TECK is chemotactic towards activated macrophages, thymocytes and dendritic cells.
Bioactivity: Determined by its ability to chemoattrract human monocytes using a concentration range of 1.0-10.0 ng/ml.
Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug). Expression System: E Coli. Breast Neoplasms, Gastrointestinal Diseases, Graft vs Host Disease, Immune System Diseases, Inflammation, Lung Diseases, Lymphoma, Necrosis, Neoplasms, Experimental, Vascular Diseases are some of the diseases may be linked to TECK protein. TECK also interacts with the following gene(s): Ccl28, Ccr7, Ccr9, Ccrl1, Cxcl12, Cxcr3, Cxcr6. Brain, Embryonic Tissue, Eye, Intestine, Lymph Node, Mammary Gland, Skin, Testis, Thymus tissues are correlated with this protein. The following patways have been known to be associated with this gene.