|The TDRD7 tdrd7 (Catalog #MBS9218026) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The TDRD7 tdrd7 product has the following accession number(s) (GI #152031705) (NCBI Accession #Q8NHU6.2) (Uniprot Accession #Q8NHU6). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis.
Cellular Location: Cytoplasm. Note: Localizes to cytoplasmic RNA granules. Present in chromatoid body (CB) of spermatids (mammalian counterpart of germplasm, pole plasm or polar granules in Drosophila germ cells), also named processing bodies (P-bodies) in somatic cells. Detected in the multilobular cytoplasmic CBs (also called intermitochondrial cementin) in pachytene spermatocytes and as a single perinuclear CB in haploid round spermatids (By similarity). Embryonic Tissue, Eye, Nerve, Ovary, Testis, Uncharacterized Tissue tissues are correlated with this protein. Cardiovascular Diseases, Cataract, Disease Models, Animal, Glaucoma, Infertility, Female, Infertility, Male are some of the diseases may be linked to TDRD7 Antibody (C-term) Blocking peptide. The following patways have been known to be associated with this gene.