TBX6 blocking peptide product blog
Tags: Blocking Peptide; TBX6; TBX6 blocking peptide;
The TBX6 tbx6 (Catalog #MBS9218753) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The TBX6 tbx6 product has the following accession number(s) (GI #115502464) (NCBI Accession #O95947.2) (Uniprot Accession #O95947). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity).
Cellular Location: Nucleus. Tissue Location: Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in adult testis, kidney, lung, muscle and thymus. TBX6 also interacts with the following gene(s): BMP4, FGF2, FGF4, FGF8, HES7, MESP2, MYOD1, SMAD6. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Lung, Muscle, Testis tissues are correlated with this protein. Abnormalities, Multiple, Atrophy, Chromosome Aberrations, Cognition Disorders, Heart Defects, Congenital, Heart Diseases, Learning Disorders are some of the diseases may be linked to TBX6 Antibody (C-term) Blocking peptide.