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Latest INO-1001 blogs from MyBioSource
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INO-1001 inhibitor product blog

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Posted on 2018-01-12 06:04:44 by mybiosource_staff
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(read more)
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INO-1001 kinase inhibitor product blog

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Posted on 2015-10-29 08:51:36 by mybiosource_staff
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The INO-1001 n/a (Catalog #MBS8506381 is a Kinase Inhibitor and is intended for research purposes only. The product is available for immediate purchase. INO-1001 is an isoindolinone derivative and potent inhibitor of the nuclear enzyme PARP (poly (ADP-ribose) polymerase) with chemosensitization and radiosensitization properties[1, 2]. INO-1001 inhibits PARP, which may result in inhibition of tumor cell DNA repair mechanisms and, so, tumor cell resistance to chemotherapy and radiation therapy. PARP enzymes are activated by DNA breaks and have been implicated in the repair of DNA single-strand breaks (SSB). In addition, INO-1001 improves the recovery of myocardial ... (read more)
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