Sulindac Sulfide small molecule product blog
Tags: Sulindac Sulfide; Small Molecule; Sulindac Sulfide small molecule;
The Sulindac Sulfide n/a (Catalog #MBS807999) is a Small Molecule produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given small molecule. We\'ve tested the Sulindac Sulfide with the following immunoassay(s):
Chemical Structure (Chemical structure of Sulindac Sulfide (SIH-261), a NFkB inhibitor. CAS #: 32004-67-4. Molecular Formula: C20H17FO2S. Molecular Weight: 340.41 g/mol.)
Sulindac is a nonsteroidal anti-inflammatory drug that is known to prevent recurrence and reduce colorectal polyps. It is a prodrug that is metabolized to a sulfide and sulfone derivative in vivo. The mechanism of action of both is the selective induction of apoptosis. The anti-inflammatory properties of sulindac are mediated by COX inhibition (1, 2).
Solubility: Soluble to 25 mM in DMSO, 3 mM in ethanol
CAS Number: 32004-67-4
Molecular Formula: C20H17FO2S
SMILES: CC\1=C(C2=C(/C1=C\C3=CC=C(C=C3)SC)C=CC(=C2)F)CC(=O)O
InChI: 1S/C20H17FO2S/c1-12-17(9-13-3-6-15(24-2)7-4-13)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-
InChI Key: LFWHFZJPXXOYNR-RQZCQDPDSA-N
PubChem CID: 1548887.