Src I1 inhibitor product blog
Tags: Inhibitor; Src I1; Src I1 inhibitor;
The Src I1 n/a (Catalog #MBS515021) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given inhibitor. We\'ve tested the Src I1 with the following immunoassay(s):
Molecular Structure
Src kinase inhibitor
Potent and selective inhibitor of Bruton\'s tyrosine kinase (BTK). Inhibits recombinant BTK with an IC50 = 2.5 uM1 and has no activity at other protein kinases (including JAK1, JAK3, HCK, EGFR kinase and insulin receptor kinase) at concentrations up to 300 uM2.
Scientific Background: Potent, competitive dual site (ATP- and substrate-binding domains) Src and Lck inhibitor (IC50 = 44 and 88 nM respectively). Also inhibits VEGFR2 and c-fms at higher concentrations (IC50 = 0.32 and 30 uM respectively).
CAS Number: 179248-59-0
Molecular Formula: C22H19N3O3. Melting Point: 243-245 degree C
Activity: BTK Inhibitor
Reconstitution: DMSO (10 mg/ml) and ethanol (15 mg/ml)
Solubilization: Soluble in DMSO (15 mg/ml); Ethanol (nil).