Src blocking peptide product blog
Tags: SRC; Blocking Peptide; SRC blocking peptide; Phospho-Src;
The Src src (Catalog #MBS544338) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Phospho-Src can be used in a range of immunoassay formats including, but not limited to, Immunocompetition, Immunodepletion.Western Blot: 1:500. Researchers should empirically determine the suitability of the Src src for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Src src product has the following accession number(s) (GI #4885609) (NCBI Accession #NP_005408.1) (Uniprot Accession #P12931). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Antigenic Blocking Peptide Phosphorylated Proto-oncogene tyrosine-protein kinase Src Antibody N-epitope
Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis migration, and transformation.
Immunogen: N-epitope phosphorylated synthetic peptide taken within amino acid region 200-300 on human Src protein. Phosphorylated Tyr-215 residue.
Expression: Expressed ubiquitously. Platelets, neurons and osteoclasts express 5-fold to 200-fold higher levels than most other tissues. Modification: Phosphorylated
Determinant: N-epitope
Molecular Function: ATP binding, ephrin receptor binding, heme binding, ion channel binding, enzyme binding, growth factor receptor binding, integrin binding, kinase activity
Subcellular Location: Cell membrane, mitochondrion inner membrane, nucleus, Cytoplasm (Note: Localizes to focal adhesion sites following integrin engagement. Localization to focal adhesion sites requires myristoylation and SH3 domain.). Breast Neoplasms, Cell Transformation, Neoplastic, Disease Models, Animal, Inflammation, Lung Neoplasms, Necrosis, Neoplasm Invasiveness, Neoplasm Metastasis, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to Phospho-Src Peptide. Blood, Bone, Brain, Embryonic Tissue, Kidney, Liver, Lung, Muscle, Nerve, Prostate tissues are correlated with this protein. The following patways have been known to be associated with this gene. Src also interacts with the following gene(s): BCAR1, CBL, CRK, EGFR, ESR1, KHDRBS1, PTK2, PTPN1, PXN, STAT3.