SOX7 blocking peptide product blog
Tags: Blocking Peptide; SOX7; SOX7 blocking peptide;
The SOX7 sox7 (Catalog #MBS9222488) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The SOX7 sox7 product has the following accession number(s) (GI #20532272) (NCBI Accession #Q9BT81.1) (Uniprot Accession #Q9BT81). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5\'- AACAAT-3\'.
Cellular Location: Nucleus. Cytoplasm. Tissue Location: Widely expressed in adult and fetal tissues. Present both in mesenchymal and epithelial cells in some adult tissues, including colon. Tends to be down-regulated in prostate adenocarcinomas and colorectal tumors due to promoter hypermethylation. The following patways have been known to be associated with this gene. Brain, Embryonic Tissue, Heart, Lung, Ovary, Pancreas, Placenta, Prostate, Stomach, Vascular tissues are correlated with this protein. Adenocarcinoma, Congenital Abnormalities, Disease Models, Animal, Edema, Heart Defects, Congenital, Intestinal Neoplasms, Liver Diseases, Liver Neoplasms, Lung Neoplasms, Prostatic Diseases are some of the diseases may be linked to SOX7 Antibody (C-term) Blocking Peptide. SOX7 also interacts with the following gene(s): CDX1, FGF3, FOXA2, GATA4, GATA6, NANOG.