SorLA blocking peptide product blog
Tags: Blocking Peptide; SORLA; SorLA blocking peptide;
The SorLA sorl1 (Catalog #MBS544499) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s SorLA can be used in a range of immunoassay formats including, but not limited to, Immunocompetition, Immunodepletion.Western Blot: 1:500. Researchers should empirically determine the suitability of the SorLA sorl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SorLA sorl1 product has the following accession number(s) (GI #341942117) (NCBI Accession #O88307.3) (Uniprot Accession #O88307). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Antigenic Blocking Peptide Sortilin-related receptor Antibody
Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. May play a role in neural organization, as well as the establishment of embryonic organ systems.
Immunogen: Synthetic Peptide
Expression: Abundant in brain, where it is mainly expressed in adult cerebellum, hippocampal ca regions, dentate gyrus, and to a much lesser extent in the cerebral cortex. Detectable in kidney, skeletal muscle, lung and spleen, but not in the liver. Molecular Function: beta-amyloid binding, low-density lipoprotein particle binding
Subcellular Location: membrane, Single-pass type I membrane protein, golgi apparatus, Secreted. Alzheimer Disease, Atherosclerosis, Cardiovascular Diseases, Cognition Disorders, Disease Models, Animal, Heart Diseases, Memory Disorders, Necrosis, Nerve Degeneration, Nervous System Diseases are some of the diseases may be linked to SorLA Antibody Antigenic Blocking Peptide. Bone, Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Muscle, Spinal Cord, Testis tissues are correlated with this protein. SorLA also interacts with the following gene(s): App, Bace1, Gga1, Gga2, Plaur, Rock2, Vps26a, Vps35.