|The SNCA snca (Catalog #MBS8232623) is a Blocking Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The Alpha-synuclein (pS129) Blocking Peptide reacts with Human, Mouse, Rat, Bovine, Monkey, Sheep and may cross-react with other species as described in the data sheet. MyBioSource\'s Alpha-synuclein can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Researchers should empirically determine the suitability of the SNCA snca for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SNCA snca product has the following accession number(s) (GI #4507109) (NCBI Accession #NP_000336.1) (Uniprot Accession #P37840). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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The peptide is used to block Anti-Alpha-synuclein Antibody reactivity.
Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Directions for Use: Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours. SNCA also interacts with the following gene(s): APP, FYN, MAPT, PARK2, PARK7, SLC6A3, SNCAIP, UBC. The following patways have been known to be associated with this gene. Brain Diseases, Disease Models, Animal, Lewy Body Disease, Movement Disorders, Nerve Degeneration, Nervous System Diseases, Neurodegenerative Diseases, PARKINSON DISEASE 1, AUTOSOMAL DOMINANT, Parkinson Disease, Parkinsonian Disorders are some of the diseases may be linked to Alpha-synuclein (pS129) Blocking Peptide. Blood, Brain, Embryonic Tissue, Eye, Heart, Kidney, Liver, Nerve, Skin, Vascular tissues are correlated with this protein.