Shb blocking peptide product blog
Tags: Blocking Peptide; SHB; SHB blocking peptide;
The Shb shb (Catalog #MBS9224146) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The Shb shb product has the following accession number(s) (GI #110816416) (NCBI Accession #Q6PD21.2) (Uniprot Accession #Q6PD21). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic- FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells (By similarity).
Cellular Location: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note: Associates with membrane lipid rafts upon TCR stimulation. Tissue Location: Expressed in heart, liver, brain and kidney (at protein level). Shb also interacts with the following gene(s): Eps8, Fgfr1, Frs2, Kdr, Ptpn11, Src, Zap70. Atherosclerosis, Carcinoma, Hepatocellular, Diabetes Mellitus, Heart Diseases, Hypertension, Inflammation, Kidney Diseases, Liver Diseases, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to Mouse Shb Antibody (C-term) Blocking Peptide. The following patways have been known to be associated with this gene. Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Muscle, Ovary, Pancreas, Skin tissues are correlated with this protein.