SFN blocking peptide product blog
Tags: SFN; Blocking Peptide; SFN blocking peptide;
The SFN sfn (Catalog #MBS9225877) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The SFN sfn product has the following accession number(s) (GI #5454052) (NCBI Accession #NP_006133.1) (Uniprot Accession #P31947). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
Cellular Location: Cytoplasm. Nucleus. Secreted. Note: May be secreted by a non-classical secretory pathway. Tissue Location: Present mainly in tissues enriched in stratified squamous keratinizing epithelium. Blood, Brain, Liver, Lung, Lymph Node, Muscle, Nerve, Prostate, Skin, Thyroid tissues are correlated with this protein. SFN also interacts with the following gene(s): AKT1, BAD, CDC25B, CDK1, MAPK1, TP53, TSC2, UBC. The following patways have been known to be associated with this gene. Adenocarcinoma, Breast Neoplasms, Carcinoma, Cardiovascular Diseases, Disease Models, Animal, Inflammation, Lung Neoplasms, Necrosis, Neoplasm Metastasis, Nervous System Diseases are some of the diseases may be linked to SFN Antibody (C-term) Blocking peptide.