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SERPINA1 inhibitor product blog

Posted on 2015-06-29 22:07:06 by mybiosource_staff
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Tags: SERPINA1; Inhibitor; a1-Antitrypsin; SERPINA1 inhibitor;
The SERPINA1 serpina1 (Catalog #MBS655470) is an Inhibitor produced from Human serum and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s a1-Antitrypsin can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA).
Suitable for use in ELISA. Researchers should empirically determine the suitability of the SERPINA1 serpina1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The SERPINA1 serpina1 product has the following accession number(s) (GI #189163542) (NCBI Accession #NP_001121179.1) (Uniprot Accession #P01009). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Alpha-1-antitrypsin is a glycoprotein of MW 54kD with a pI of 4.8. It is a serine protease inhibitor that acts to limit the amount of cell damage and death at the tissue site. Different isoenzymes exist which together form the Protease inhibitor system. Phenotype M is the most common and certain variants (S and Z) are associated with A1AT deficiency which can lead to emphysema and liver disease.

SERPINA1 serpina1

Blood, Bone, Heart, Intestine, Kidney, Liver, Lung, Pancreas, Skin, Vascular tissues are correlated with this protein. Carcinoma, Hepatocellular, Cardiovascular Diseases, Inflammation, Liver Cirrhosis, Liver Diseases, Liver Neoplasms, Lung Diseases, Pulmonary Disease, Chronic Obstructive, Pulmonary Emphysema, alpha 1-Antitrypsin Deficiency are some of the diseases may be linked to a1-Antitrypsin, Human (alpha-1-Antitrypsin, Alpha-1-AT, A1A, A1AT, AAT, Alpha-1-antiproteinase, Alpha-1 Protease Inhibitor, Alpha1 Proteinase Inhibitor, Alpha1 PI, MGC23330, MGC9222, PRO2275, Protease Inhibitor 1 (Anti-elastase), PI, PI1, Serpin Peptidase. The following patways have been known to be associated with this gene.
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