|The rVEGFC vegfa (Catalog #MBS142139) is a Recombinant Protein produced from Sf9 Insect Cells and is intended for research purposes only. The product is available for immediate purchase.
The rVEGFC vegfa product has the following accession number(s) (GI #160358797) (NCBI Accession #NP_001103804.1) (Uniprot Accession #P16612). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
DTVKLAAAHY NTEILKSIDN EWRKTQCMPR EVCIDVGKEF GAATNTFFKP PCVSVYRCGG CCNSEGLQCM NTSTGYLSKT LFEITVPLSQ GPKPVTISFA NHTSCRCMSK LDVYRQVHSI IHHHHHH .
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Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Vascular Endothelial Growth Factor are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Solubility: It is recommended to reconstitute the lyophilized Vascular Endothelial Growth Factor C in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity: Measured by its ability to stimulate phosphorylation of the VEGFR-3/FLT-4 receptor in porcine aortic endothelial cells. The ED50 for this effect is typically 200-300ng/ml corresponding to a Specific Activity of 3,334-5,000IU/mg. Choroidal Neovascularization, Diabetic Retinopathy, Heart Diseases, Inflammation, Lung Diseases, Macular Degeneration, Macular Edema, Neoplasm Metastasis, Neovascularization, Pathologic, Retinal Diseases are some of the diseases may be linked to Recombinant Rat Vascular Endothelial Growth Factor Related Protein. The following patways have been known to be associated with this gene. Brain, Colon, Connective Tissue, Embryonic Tissue, Eye, Heart, Liver, Lung, Muscle, Placenta tissues are correlated with this protein.