|The rSDF 1b cxcl12 (Catalog #MBS143642) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase.
The rSDF 1b cxcl12 product has the following accession number(s) (GI #10834988) (NCBI Accession #NP_000600.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Stromal Cell-Derived Factor-1 beta are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Solubility: It is recommended to reconstitute the lyophilized SDF-1b in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity: The specific activity as determined by its ability to chemoattract human peripheral blood monocytes at 100-150ng/ml corresponding to a Specific Activity of 6,667-10,000IU/mg. Bone, Bone Marrow, Brain, Embryonic Tissue, Heart, Liver, Lung, Muscle, Nerve, Vascular tissues are correlated with this protein. rSDF 1b also interacts with the following gene(s): CCR4, CCR5, CXCR3, CXCR4, CXCR7, HIF1A, JAK2, SDC4, STAT3, VAV1. The following patways have been known to be associated with this gene. Breast Neoplasms, Cardiovascular Diseases, HIV Infections, Heart Diseases, Inflammation, Ischemia, Lung Diseases, Necrosis, Neoplasm Invasiveness, Neoplasm Metastasis are some of the diseases may be linked to Recombinant Rat Stromal Cell-Derived Factor-1 beta (CXCL12).