RAPGEF1 blocking peptide product blog
Tags: Blocking Peptide; RAPGEF1; RAPGEF1 blocking peptide;
The RAPGEF1 rapgef1 (Catalog #MBS9230028) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The RAPGEF1 rapgef1 product has the following accession number(s) (GI #143811452) (NCBI Accession #Q13905.3) (Uniprot Accession #Q13905). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.
Cellular Location: Early endosome. Tissue Location: Ubiquitously expressed in adult and fetus. Expression is high in adult skeletal muscle and placenta and in fetal brain and heart. Low levels of expression in adult and fetal liver. RAPGEF1 also interacts with the following gene(s): HCK, RAP1A, RAP1B, SRC. Blood, Brain, Embryonic Tissue, Lung, Muscle, Ovary, Spleen, Vascular tissues are correlated with this protein. Carcinoma, Inflammation, Mental Disorders, Necrosis, Nervous System Diseases, Vascular Diseases are some of the diseases may be linked to RAPGEF1 Blocking Peptide (Center). The following patways have been known to be associated with this gene.