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Rapamycin inhibitor product blog

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Posted on 2017-03-03 19:07:49 by mybiosource_staff
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Tags: Inhibitor; Rapamycin; Rapamycin inhibitor;
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The Rapamycin n/a (Catalog #MBS515013) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given inhibitor. We\'ve tested the Rapamycin with the following immunoassay(s):
Molecular Structure
Molecular Structure Rapamycin.

mTOR inhibitor
Selective inhibitor of IKK, IC50=11.2 M. Inhibits transcription of NF B-dependent genes in an IL-1 -induced rheumatoid arthritis model1. Displays anti-inflammatory activity. Reverses the anti-adipogenic effect of PDGF on human preadipocytes2. Cell permeable and reversible.

Scientific Background: Potent immunosuppressant. The rapamycin-FKBP12 complex binds to and inhibits mTOR (1). Inhibits IL-2-induced activation of p70 S6 kinase (2). Extends lifespan of mice (3). Induces autophagy in a variety of cell lines (4).

CAS Number: 53123-88-9
Molecular Formula: C51H79NO13. Melting Point: 209-211 degree C
Activity: IKK-2 inhibitor
Reconstitution: May be dissolved in DMSO (25 mg/ml); Ethanol (2 mg/ml)
Solubilization: Soluble in DMSO (50 mg/ml); or Ethanol (50 mg/ml).
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