|The RAP rap (Catalog #MBS537514) is a Recombinant Protein produced from Rat and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s RAP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), SDS-PAGE, Electrophoresis, BIAcore, ELISA (EIA).
Ligand binding to RAP is calcium-dependent. Lipid receptors may be released from RAP by using a buffer containing 10 mM EDTA. Buffers containing phosphate should not be used as it forms precipitates with calcium. Researchers should empirically determine the suitability of the RAP rap for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The RAP rap product has the following accession number(s) (GI #2661436) (NCBI Accession #CAA05085.1) (Uniprot Accession #O57378). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including RAP are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Protein Type: Recombinant
Biological Significance: Low density lipoprotein receptor-related protein associated protein 1 also known as LRPAP1 or RAP is a chaperone protein which in humans is encoded by the LRPAP1 gene. RAP is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Expression System: E Coli
Tag/Conjugate: His-myc tag. RAP also interacts with the following gene(s): APBB1IP, LRP1B, LRP2, LRP8, RAPGEF1, RAPH1, SORL1, TERF2IP, VLDLR. Brain Diseases, Cell Transformation, Neoplastic, Death, Edema, Hemorrhage, Hypertension, Hypertrophy, Inflammation, Kidney Diseases, Necrosis are some of the diseases may be linked to RAP protein (Rat). Brain, Embryonic Tissue, Gonad, Head, Heart, Limb, Liver, Muscle, Ovary, Testis tissues are correlated with this protein.