Pyroxamide kinase inhibitor product blog
Tags: Kinase Inhibitor; Pyroxamide; Pyroxamide kinase inhibitor;
The Pyroxamide n/a (Catalog #MBS8506221) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given inhibitor. We\'ve tested the Pyroxamide (NSC 696085) with the following immunoassay(s):
Testing Data
Sumanirole maleate is a highly selective D2 receptor full agonist with an ED50 of about 46 nM. It has greater than 200-fold selectivity for the D2 receptor subtype versus the other dopamine receptor subtypes in radioligand binding assays. In cell-based assays, sumanirole is a fully efficacious agonist, with EC50 values between 17 and 75 nM. In animals, sumanirole elicits many physiological responses attributed to D2-like receptor function. In rats, sumanirole is a full agonist for elevation of striatal acetylcholine levels (ED50 = 12.1 mumol/kg i.p.). Sumanirole s.c. dose dependently decreased plasma prolactin levels and depressed dopamine neuron firing rates in the substantia nigra pars compacta with an ED50 of 2.3 mumol/kg i.v. [1][2].
Formula: C11H13N3O.C4H4O4
CAS Number: 179386-44-8.