PTPN1 blocking peptide product blog
Tags: PTPN1; Blocking Peptide; PTP1B; PTPN1 blocking peptide;
The PTPN1 ptpn1 (Catalog #MBS9227626) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The PTPN1 ptpn1 product has the following accession number(s) (GI #4506289) (NCBI Accession #NP_002818) (Uniprot Accession #P18031). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
Cellular Location: Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side Note: Interacts with EPHA3 at the cell membrane. Blood, Brain, Connective Tissue, Heart, Kidney, Liver, Lung, Muscle, Pancreas, Vascular tissues are correlated with this protein. Breast Neoplasms, Diabetes Mellitus, Type 2, Disease Models, Animal, Glucose Intolerance, Hyperglycemia, Inflammation, Insulin Resistance, Liver Diseases, Necrosis, Weight Gain are some of the diseases may be linked to PTP1B Antibody (N-terminal) Blocking Peptide. PTPN1 also interacts with the following gene(s): AKT1, BCAR1, EGFR, GRB2, INSR, IRS1, JAK2, SRC, TRPV6, TYK2. The following patways have been known to be associated with this gene.