|The Prl prl (Catalog #MBS142198) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase.
The Prl prl product has the following accession number(s) (GI #130934) (NCBI Accession #P06879.1) (Uniprot Accession #P06879). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
The sequence of the first five N-terminal amino acids was determined and was found to be Met-Leu-Pr o-Ile-Cys.
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Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Prolactin are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Solubility: It is recommended to reconstitute the lyophilized Prolactin in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of rat lymphoma, Nb2-11 was found to be < 0.065 ng/ml corresponding to a specific activity of 15,400,000 Units/mg. Brain, Embryonic Tissue, Pituitary Gland, Spinal Cord, Uncharacterized Tissue tissues are correlated with this protein. Prl also interacts with the following gene(s): Ghr, Jak2, Lep, Pou1f1, Prlr, Stat1, Stat3, Stat5a, Trh. The following patways have been known to be associated with this gene.